How to use
A simple guide to taking Doxy-PEP correctly so it works when you need it.
The recommended dose is 200mg of doxycycline (usually two 100mg tablets), taken as soon as possible—and no later than 72 hours—after having condomless sex.
Recommended dosage & frequency
- Dosage: 200mg of doxycycline (usually two 100mg tablets)
- Take as soon as possible—and no later than 72 hours—after condomless sex
- Do not exceed 200mg in any 24-hour period
- If you have sex again within 24 hours, take another dose 24 hours after your last dose
What it helps prevent
Doxy-PEP is intended to reduce the risk of acquiring certain bacterial STIs, specifically:
- Chlamydia
- Gonorrhea
- Syphilis
Doxy-PEP 101
The essentials of using doxycycline as post-exposure prophylaxis—from dosing to what it protects against.
More Questions?
Post-exposure protection, made simple
Doxy-PEP (doxycycline) is a post-exposure prophylaxis that helps prevent bacterial STIs such as syphilis, chlamydia, and gonorrhea by up to 80%. It is taken as soon as possible—and no later than 72 hours—after condomless sex. It is intended to reduce the risk of acquiring certain bacterial STIs, specifically chlamydia, gonorrhea, and syphilis.Important to know
- Take Doxy-PEP only as directed by a healthcare professional.
- It is most effective when taken as soon as possible after condomless sex—and no later than 72 hours.
- Do not exceed 200mg of doxycycline in any 24-hour period.
- Doxy-PEP reduces but does not eliminate the risk of bacterial STIs; it does not protect against HIV or viral STIs.
- Continue regular STI screening as recommended by your healthcare provider.
- Doxycycline can also treat bacterial skin infections such as acne, rosacea, cellulitis, impetigo and certain MRSA infections—always under medical guidance.
Common questions about Doxy-PEP
Often bought together
-
PrEP On-demand
Price range: $30 through $38 -
PrEP – Starter Kit
Price range: $60 through $175 -
PrEP Daily
Price range: $48 through $121 -
PrEP Daily & Doxy-PEP Subscription
Price range: $176 through $426 -
HIV Self Test-Kit (Oral)
$17
-
PrEP On-demand
Price range: $30 through $38 -
PrEP – Starter Kit
Price range: $60 through $175 -
PrEP Daily
Price range: $48 through $121 -
PrEP Daily & Doxy-PEP Subscription
Price range: $176 through $426 -
HIV Self Test-Kit (Oral)
$17
Doxy-PEP: discreet, on-demand STI protection.
Privacy mattered most to me. Ordering Doxy-PEP online and receiving it discreetly meant I could protect myself without a clinic visit.
I travel a lot and don’t always plan ahead. Keeping Doxy-PEP on hand gave me peace of mind for those spontaneous moments.
I liked that it was straightforward — take it soon after, not more than 200mg in 24 hours. Simple to follow and easy to fit into my life.
The packaging was discreet, which really mattered to me. Nothing about the delivery drew attention, and I could take it when I was ready.
Knowing Doxy-PEP can cut syphilis and chlamydia risk significantly made me feel more in control of my sexual health.
I appreciated that the information explained what it does and doesn’t protect against. It helped me understand it’s part of a bigger picture.
My clinician explained the 24-hour rule clearly. Knowing when to take a second dose after sex again gave me confidence I was doing it right.
This was my first time using Doxy-PEP, so I had plenty of questions. The plain-language explanations made it feel manageable rather than clinical.
As a gay man, I’ve sometimes felt judged discussing sexual health. Ordering Doxy-PEP privately let me look after myself without that added pressure.
I wasn’t sure how soon after sex I could take it. The 72-hour window guidance helped me act in time and not second-guess myself.
I’d put off getting anything for after-exposure protection because I assumed it would be complicated. Doxy-PEP was far simpler than I expected.
Privacy mattered most to me. Ordering Doxy-PEP online and receiving it discreetly meant I could protect myself without a clinic visit.
I travel a lot and don’t always plan ahead. Keeping Doxy-PEP on hand gave me peace of mind for those spontaneous moments.
I liked that it was straightforward — take it soon after, not more than 200mg in 24 hours. Simple to follow and easy to fit into my life.
The packaging was discreet, which really mattered to me. Nothing about the delivery drew attention, and I could take it when I was ready.
Knowing Doxy-PEP can cut syphilis and chlamydia risk significantly made me feel more in control of my sexual health.
I appreciated that the information explained what it does and doesn’t protect against. It helped me understand it’s part of a bigger picture.
My clinician explained the 24-hour rule clearly. Knowing when to take a second dose after sex again gave me confidence I was doing it right.
This was my first time using Doxy-PEP, so I had plenty of questions. The plain-language explanations made it feel manageable rather than clinical.
As a gay man, I’ve sometimes felt judged discussing sexual health. Ordering Doxy-PEP privately let me look after myself without that added pressure.
I wasn’t sure how soon after sex I could take it. The 72-hour window guidance helped me act in time and not second-guess myself.
I’d put off getting anything for after-exposure protection because I assumed it would be complicated. Doxy-PEP was far simpler than I expected.
Pride Health is Asia’s leading LGBTQ+ digital health platform. Founded in Singapore and operating out of Bangkok, Thailand, delivering inclusive healthcare consults and support to Southeast Asia and selected parts of Europe








